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How to buy Fycompa (perampanel): You can order Fycompa (perampanel) from TheSocialMedwork if the drug has not been approved or is not available in your country. We help patients and doctors get access to medicines at the lowest price worldwide.
Marketing Authorisation Holder
Eisai Europe Ltd
Mode of Action
AMPA receptor antagonist
Regulatory agency approval
European Medical Agency (EMA), European Union, Food and Drug Administration (FDA), USA, Therapeutic Goods Administration (TGA), Australia
Fycompa (perampanel) is an antiepileptic medicine used to treat adults and children from 12 years of age with partial-onset seizures (epileptic fits) with or without secondary generalisation1.
How does Fycompa (perampanel) work?
Epilepsy is caused by excessive electrical activity in the brain. Although the precise mechanism by which Fycompa (perampanel) works is not fully understood, it is thought to block the action of the neurotransmitter glutamate. Neurotransmitters are naturally-occurring chemicals in the nervous system that allow nerve cells to communicate with each other. Glutamate is the main stimulatory neurotransmitter in nerve cells which can trigger and maintain seizures. Therefore by blocking glutamate’s actions, Fycompa (perampanel) is thought to stop epileptic seizures from occurring1.
Where has Fycompa (perampanel) been approved?
Fycompa (perampanel) was approved for the treatment of partial-onset seizures in adults and children older than 12 years of age by:
FDA (USA) October 22, 20125
EMA (EU) on July 07, 20121
TGA (AUS) on May 23, 20144
How is Fycompa (perampanel) taken?
The standard dosage of Fycompa (perampanel) is:
at the start of treatment 2 mg per day
if it is well tolerated it may be progressively increased by increments of 2 mg/day to a maximum dose of 12 mg per day1.
Patients should be monitored for signs of suicidal ideation and behaviours and appropriate treatment should be considered2,3,4.
Complete information about Fycompa (perampanel) dosage and administration can be in the resources section.
Consult your treating doctor for personalised dosing.
Are there any known side effects of Fycompa (perampanel)?
The approvals were based on several studies that have shown Fycompa (perampanel) to be more effective than placebo in reducing the frequency of epileptic seizures1,3. In one study, the percentage of patients who experienced a decrease in seizure frequency of at least 50% was 37.6% for patients taking 8 mg Fycompa (perampanel) and 36.1% for patients taking 12 mg Fycompa (perampanel), compared with 26.4% of patients taking placebo. In another study, 33.3% and 33.9% of patients taking 8 mg and 12 mg Fycompa (perampanel) respectively showed a decrease in seizure frequency of at least 50%, compared with 14.7% of patients taking placebo. A third study showed a significant decrease in seizure frequency only in patients taking 4 mg and 8 mg Fycompa but not in patients taking a dose of 2 mg1.
For patients with primary generalised tonic-clonic seizures, a type of generalized seizure that affects the entire brain, Fycompa (perampanel) was also more effective than placebo: 58% of the patients given Fycompa (perampanel) had at least a 50% reduction in frequency of seizures, compared with 36% of those given the dummy treatment. Supportive evidence from patients treated for up to 2 years suggested that the benefit was maintained with longer treatment and that some patients could benefit from doses up to 12 mg1.
During the transaction process I was very well informed by the TheSocialMedwork team. They have put as much of their effort to offer best service to me. Moreover the medicine I have ordered was imported two weeks earlier then it was expected. I highly recommend The Social Med Work.
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You always need a prescription from a doctor based in your country. Other documents, such as an import license from the Ministry of Health, may be needed and depend on your country’s regulations. Contact us and we will provide you with all of the information about the required documents needed for your country.
For prescription medicines you will always need a prescription from your treating doctor. This is to ensure that your treatment is monitored and led by a doctor who is responsible for administering the medicine to you. The prescription is the evidence that your doctor gives you their medical support.
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Yes. TheSocialMedwork is registered with the Dutch Ministry of Health as an independent medicines intermediary (registration number 6730 BEM). We always follow your country’s laws and regulations and will discuss any legal requirements with you. We only ship medicines when our patients have a prescription from their treating doctor.By using TheSocialMedwork you will receive genuine medicines in perfect condition, no matter where you live.
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Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Medicine information contained herein may be time sensitive. The absence of a warning for a given medicine or combination thereof in no way should be construed to indicate that the medicine or combination is safe, effective or appropriate for any given patient. Always consult your treating physician before starting a course of treatment.