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Bavencio (avelumab)

How to buy Bavencio:
You can order Bavencio (avelumab) via TheSocialMedwork if the drug has not been approved and/or is not available in the patient’s country. TheSocialMedwork – helping patients and doctors access the latest approved medicines and at the lowest price possible worldwide.

Manufacturer EMD Serono Inc.
Disease Skin Cancer
Indication Metastatic Merkel cell carcinoma (MCC)
Mode of action PD-L1 blocking antibody (immunotherapy)
Approval Status FDA Approved (USA)
Shipping Type Cold Chain (2°C to 8°C)

Who is avelumab for?

Bavencio (avelumab) is indicated for the treatment of adults and pediatric patients 12 years and older with metastatic Merkel cell carcinoma (MCC) [1]. This is the first FDA-approved treatment for this rare, aggressive form of skin cancer [2].

Recommended dose

Complete information about Bavencio (avelumab) dosage and administration can be found here: [1].

The standard dosage is:

  • 10 mg/kg as an intravenous infusion over 60 minutes every 2 weeks.

Consult your treating doctor for personalised dosing.

What is avelumab and how does it work?

Bavencio (avelumab) is a programmed death ligand-1 (PD-L1) blocking antibody indicated for the treatment of adults and pediatric patients 12 years and older with metastatic Merkel cell carcinoma (MCC) [1].

Bavencio (avelumab) targets the PD-1/PD-L1 pathway (proteins found on the body’s immune cells and some cancer cells) [2].

PD-1 receptors are found on certain cells of the immune system called T cells. Cancer cells can produce proteins (PD-L1 and PD-L2) that attach to this receptors, switching off the T cells. By attaching to the PD-1 receptors Bavencio (avelumab) prevents cancer cells from switching off T cells, thereby increasing the ability of the immune system to kill cancer cells [1].

What is avelumab’s approval status?

Bavencio (avelumab) was approved by:

  • FDA (US) on March 23, 2017,

for metastatic Merkel cell carcinoma (MCC) [1].

The approval was based on a study (JAVELIN Merkel 200 trial) involving 88 patients with metastatic MCC whose disease had progressed on, or after chemotherapy was administered for distant metastatic disease. The overall response rate was 33 % (95 % CI: 23.3, 43.8) with 11.4 % complete responses. The duration of response ranged from 2.8 months to over 23.3 months, with 86 % of patients having a response that lasted for at least 6 months and 45 % of patients having a response that lasted for at least 12 months [1].

References

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5,017.505,318.55
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Handling Fee €295
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How to order an overseas approved medicine from TheSocialMedwork.

Ordering with TheSocialMedwork is a safe and legal way to import a prescription medicine that has been approved in another country, but is not yet available where you live.

1. Enquire

If you think that this medicine may be suitable for treating your condition, get in touch. We’ll answer any questions you might have and provide you with further information. Click on the calculate price tab to get a close estimate of the full cost of the medicine including delivery. If you would like us to provide you with a precise quote we’ll need to know the exact address of where you would like us to send your medicine to.

2. Chat with your doctor

About whether this treatment might be suitable for you. In order to place an order with us, you’ll need to provide us with a prescription from your doctor who must be based in the same country where the medicine will be shipped to.

3. Place your order

Once you have your doctor’s prescription you’re ready to place an order with us. Payment can be made by credit card, electronic bank transfer or paypal.

4. Delivery

As soon as we receive your payment we’ll process your order and your medicine will be shipped to you via a pharmacy. Delivery time can vary from country to country but usually takes 1 to 3 weeks. We’ll send you a tracking number and keep you up to date on the status of your order.

 

Rest assured that we’ll guide you through the entire process. We’ll let you know exactly what regulations need to be followed and the specific documentation you’ll need to import the medicine into your country so that you get your treatment as quickly as possible.

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