Product Catalog [{"id":"368","name":"Edaravone","price":474.5,"sku":"Edaravone Meiji Seika","brand":"Meiji Seika Pharma Co., Ltd.","position":1,"category":"Diseases\/Neurology\/Amyotrophic Lateral Sclerosis (ALS)"},{"id":"292","name":"Ketas","price":469,"sku":"Ketas (ibudilast)","brand":"Kyorin Pharmaceuticals Co","position":2,"category":"Diseases\/Neurology\/Amyotrophic Lateral Sclerosis (ALS)"},{"id":"291","name":"Clenbuterol","price":102.57,"sku":"Clenbuterol","brand":"Harasawa","position":3,"category":"Diseases\/Neurology\/Amyotrophic Lateral Sclerosis (ALS)"},{"id":"274","name":"Tudcabil","price":22.3,"sku":"Tudcabil (tauroursodeoxycholic acid)","brand":"Bruschettini s.r.l.","position":4,"category":"Diseases\/Neurology\/Amyotrophic Lateral Sclerosis (ALS)"},{"id":"261","name":"Nuedexta","price":1924,"sku":"Nuedexta (dextromethorphan HBr and quinidine sulfate)","brand":"Avanir Pharmaceuticals","position":5,"category":"Diseases\/Neurology\/Amyotrophic Lateral Sclerosis (ALS)"},{"id":"259","name":"Ammonaps","price":1235,"sku":"Ammonaps (sodium phenylbutyrate)","brand":"Immedica Pharma AB","position":6,"category":"Diseases\/Neurology\/Amyotrophic Lateral Sclerosis (ALS)"},{"id":"93","name":"Glentek\/Riluzol","price":124.79,"sku":"Glentek Riluzol (riluzole)","brand":"Glentek","position":7,"category":"Diseases\/Neurology\/Amyotrophic Lateral Sclerosis (ALS)"},{"id":"92","name":"Rilutek","price":230,"sku":"Rilutek (riluzole)","brand":"Sanofi - Aventis Groupe","position":8,"category":"Diseases\/Neurology\/Amyotrophic Lateral Sclerosis (ALS)"},{"id":"57","name":"Radicut","price":973,"sku":"Radicut (edaravone)","brand":"Mitsubishi Tanabe Pharma Co., Ltd. ","position":9,"category":"Diseases\/Neurology\/Amyotrophic Lateral Sclerosis (ALS)"}]

Amyotrophic Lateral Sclerosis (ALS) access options

What is ALS?

Amyotrophic lateral sclerosis (ALS), sometimes also referred to as Lou Gehrig’s disease or Motor Neurone Disease (MND), is a rapidly progressive, invariably fatal neurological disease that attacks the nerve cells responsible for controlling voluntary muscles, the motor neurons. With ALS, motor neurons degenerate or die, and stop sending messages to muscles. Unable to function, the muscles gradually weaken until the brain eventually loses its ability to start and control voluntary movement. Gradually all voluntary muscles are affected, and patients lose their strength and ability to move their arms, legs, and body. When muscles in the diaphragm and chest wall fail, the patient loses his or her ability to breathe and ventilatory support is needed1.

What is the prognosis of ALS?

Most people with ALS die from respiratory failure, usually within 3 to 5 years from the onset of symptoms1. However, about 10% of ALS patients survive for 10 or more years1. A smaller group of about 5% of people with ALS have been able to survive for 20 years or more2.

Who gets ALS?

ALS is more common in the 40 to 70 years old age group with a higher incidence in people aged over 503.

"Among studies reporting this data, the mean ± standard deviation (SD) age for ALS disease onset was 61.8 ± 3.8 years (range 54–67); mean ± SD age for ALS diagnosis was 64.4 ± 2.9 years (range 58–68). The mean ± SD diagnostic delay was 12.6 ± 2.6 months (range 8.6–16.8)." – Global Epidemiology of Amyotrophic Lateral Sclerosis
About 5 to 10% of all ALS cases are familial (inherited) with the remaining 90% sporadic. Although classified as a rare disease based on its prevalence, ALS is in fact quite common. There are approximately 140,000 new cases diagnosed worldwide each year3.

Is there a cure for ALS?

Unfortunately there is currently no cure for ALS. However, as stated by medical centre the Mayo Clinic:

"Treatments can't reverse the damage of amyotrophic lateral sclerosis, but they can slow the progression of symptoms, prevent complications and make you more comfortable and independent."  – Mayo Clinic
Treatments are designed to relieve symptoms and improve the quality of life for individuals. Supportive care is best provided by multidisciplinary teams of healthcare professionals such as physicians, pharmacists, physical, occupational, and speech therapists, nutritionists and social workers and home care and hospice nurses, who can design an individualised plan of medical and physical therapy and provide special equipment aimed at keeping patients as mobile and comfortable as possible2

Are there any medications available for ALS?

There are two medications that have been approved by major regulatory bodies like the United States' Food and Drug Administration (FDA) for the treatment of ALS:

  1. Edaravone (Radicut/Radicava) – This medication was approved under the name Radicava by the FDA in May 2017 and under the name Radicut by the Japanese Pharmaceuticals and Medical Devices Agency (PMDA) in June 2015 for treatment of ALS. It was shown to slow down the progression of the disease in some patients during clinical trials. Edaravone is administered via intravenous infusion (typically 10–14 days in a row, once a month), and side effects may include bruising, gait disturbance, hives, swelling and shortness of breath.

  2. Riluzole – This was the first ever drug approved to treat ALS and appears to slow the disease's progression in some people. Riluzole is taken as a pill and may cause side effects such as dizziness, gastrointestinal conditions and decreased lung function4. Please note: Although not listed on our website, TheSocialMedwork can make this medicine available to patients that cannot access it.

Potential new treatments for ALS

New studies and research on promising medications occur all of the time, and when a new medication is approved by a major regulatory authority, TheSocialMedwork endeavour to make it available to patients globally as quickly as possible.

Other therapies

Whilst most medicines for ALS manage symptoms of the disease as it worsens, there are non-medicinal therapies that can help patients, such as physical therapy to keep your muscles stronger for longer, aqua therapy to ease muscle spasms, and modifying one's diet when swallowing becomes affected5


1. Amyotrophic Lateral Sclerosis (ALS) Fact Sheet,
NINDS, cited on January 2018.

2. Are there any treatments for ALS
WebMD, cited on January 2018.

3. What is ALS?
ALS MND Alliance, cited on January 2018.

4. Rilutek (riluzole) - Highlights of prescribing information
Access data, FDA, cited on January 2018.

5. Amyotrophic Lateral Sclerosis
Mayo Clinic, cited on January 2018.

Further Resources
1. Global Epidemiology of Amyotrophic Lateral Sclerosis.
Chiò et al.,  Neuroepidemiology, 2013.

2. What is ALS?
ALS Association.
  1. Edaravone
    Edaravone (Meiji Seika)
    Amyotrophic Lateral Sclerosis (ALS), Cerebral Infarction
  2. Ketas
    Ketas (ibudilast)
    Amyotrophic Lateral Sclerosis (ALS), Cerebral Infarction
  3. Clenbuterol
    Amyotrophic Lateral Sclerosis (ALS)
  4. Tudcabil
    Tudcabil (tauroursodeoxycholic acid)
    Amyotrophic Lateral Sclerosis (ALS)
  5. Nuedexta
    Nuedexta (dextromethorphan HBr and quinidine sulfate)
    Amyotrophic Lateral Sclerosis (ALS), Multiple Sclerosis, Pseudobulbar Affect (PBA)
  6. Ammonaps
    Ammonaps (sodium phenylbutyrate)
    Amyotrophic Lateral Sclerosis (ALS)
  7. Glentek/Riluzol
    Glentek/Riluzol (riluzole)
    Amyotrophic Lateral Sclerosis (ALS)
  8. Rilutek
    Rilutek (riluzole)
    Amyotrophic Lateral Sclerosis (ALS)
  9. Radicut
    Radicut (edaravone)
    Amyotrophic Lateral Sclerosis (ALS), Cerebral Infarction
  10. Edaravone
    Edaravone (Daiichi Sankyo)
    Amyotrophic Lateral Sclerosis (ALS), Cerebral Infarction
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