Amyotrophic Lateral Sclerosis (ALS)
What is ALS?
What is the prognosis of ALS?Most people with ALS die from respiratory failure, usually within 3 to 5 years from the onset of symptoms1. However, about 10% of ALS patients survive for 10 or more years1. A smaller group of about 5% of people with ALS have been able to survive for 20 years or more2.
Who gets ALS?ALS is more common in the 40 to 70 years old age group with a higher incidence in people aged over 503.
"Among studies reporting this data, the mean ± standard deviation (SD) age for ALS disease onset was 61.8 ± 3.8 years (range 54–67); mean ± SD age for ALS diagnosis was 64.4 ± 2.9 years (range 58–68). The mean ± SD diagnostic delay was 12.6 ± 2.6 months (range 8.6–16.8)." – Global Epidemiology of Amyotrophic Lateral Sclerosis
Is there a cure for ALS?
Unfortunately there is currently no cure for ALS. However, as stated by medical centre the Mayo Clinic:
"Treatments can't reverse the damage of amyotrophic lateral sclerosis, but they can slow the progression of symptoms, prevent complications and make you more comfortable and independent." – Mayo Clinic
Are there any medications available for ALS?There are two medications that have been approved by major regulatory bodies like the United States' Food and Drug Administration (FDA) for the treatment of ALS:
- Edaravone (Radicut/Radicava) – This medication was approved under the name Radicava by the FDA in May 2017 and under the name Radicut by the Japanese Pharmaceuticals and Medical Devices Agency (PMDA) in June 2015 for treatment of ALS. It was shown to slow down the progression of the disease in some patients during clinical trials. Edaravone is administered via intravenous infusion (typically 10–14 days in a row, once a month), and side effects may include bruising, gait disturbance, hives, swelling and shortness of breath.
- Riluzole – This was the first ever drug approved to treat ALS and appears to slow the disease's progression in some people. Riluzole is taken as a pill and may cause side effects such as dizziness, gastrointestinal conditions and decreased lung function4. Please note: Although not listed on our website, TheSocialMedwork can make this medicine available to patients that cannot access it.
Potential new treatments for ALSNew studies and research on promising medications occur all of the time, and when a new medication is approved by a major regulatory authority, TheSocialMedwork endeavour to make it available to patients globally as quickly as possible.
NINDS, cited on January 2018.
2. Are there any treatments for ALS
WebMD, cited on January 2018.
3. What is ALS?
ALS MND Alliance, cited on January 2018.
4. Rilutek (riluzole) - Highlights of prescribing information
Access data, FDA, cited on January 2018.
5. Amyotrophic Lateral Sclerosis
Mayo Clinic, cited on January 2018.
2. What is ALS?
- Radicut (edaravone) — FDA approved under the brand name Radicava
by Mitsubishi Tanabe Pharma Co., Ltd. for Amyotrophic Lateral Sclerosis (ALS), Cerebral Infarction€992.00