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Multiple Sclerosis

Available treatments for Multiple Sclerosis
You can order a treatment for Multiple Sclerosis via TheSocialMedwork if it has not been approved and/or is not available in the patient's country. TheSocialMedwork - helping patients and doctors access the latest approved medicines and at the lowest price possible worldwide.
Read more about Multiple Sclerosis below.
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by: Merck Serono
for: Multiple Sclerosis
from: 2723.20
• EMA approved (EU)
• TGA approved (AUS)

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by: Roche
for: Multiple Sclerosis
from: 8682.50
• EMA approved (EU)
• FDA approved (USA)
• TGA approved (AUS)

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by: Biogen Idec Ltd
for: Multiple Sclerosis
from: 2173.50
• EMA approved (EU)
• FDA approved (USA)
• TGA approved (AUS)

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We may still be able to get it for you, provided that:

• it hasn't been approved and/or isn't available in your country
• you and your treating doctor have evaluated that the medicine is suitable for you, and your doctor writes a prescription for it.

About multiple sclerosis

Medicines available to help manage multiple sclerosis (MS):

What is multiple sclerosis (MS)?

MS is a chronic, inflammatory, autoimmune disease of the central nervous system that disrupts communication between the brain and other parts of the body. It is among the most common causes of neurological disability in young adults and occurs two to three times as much in women than men [1]. For most people with MS, episodes of worsening function (relapses) are initially followed by recovery periods (remissions). Over time, recovery may be incomplete, leading to progressive decline in function and increased disability [1]. Most patients experience their first symptoms of MS between the ages of 20 and 40 [2].

The cause of MS is still unknown [6]. Most researchers believe the cause is the body’s immune system incorrectly attacking and damaging myelin, the protective sheath around the nerve cells in the central nervous system (the brain and spinal cord). Repeated bouts of inflammation can leave a small scar (sclerosis) which can permanently damage nerve fibres. In a typical person with MS, many (multiple) small areas of scarring form in the nerve cells [4]. The damage can results in a difficult or impeded signalling between the brain and the rest of the body [4]. It is hypothesised that such assaults may be linked to an unknown environmental trigger, perhaps a virus [2][6].

It is estimated that about 2.5 million people around the world have MS [3].

What are the symptoms?

MS can be difficult to diagnose. Since there is no single diagnostic test for MS, the diagnosis can be difficult, delayed or even incorrect. Symptoms are very varied: each person’s experience of MS is different and most people will only experience a small number of all the possible symptoms [14].

According to the MS Trust, the "most common symptoms around the time of diagnosis are fatigue (a kind of exhaustion which is out of all proportion to the task undertaken), stumbling more than before, unusual feelings in the skin (such as pins and needles or numbness), slowed thinking or problems with eyesight."

Is MS becoming more common?

"Although more people are being diagnosed with MS today than in the past, the reasons for this are not clear. Likely contributors, however, include greater awareness of the disease, better access to medical care and improved diagnostic capabilities. There is no definitive evidence that the rate of MS is generally on the increase." - National Multiple Sclerosis Society

At which age do MS symptoms appear? 
Less than 1 in 100 people with multiple sclerosis (MS) will experience symptoms before the age of 10. However, between 2 - 5  in every 100 people experience their first symptoms before the age of 18. Most people are diagnosed between the ages of 20 and 40 but the number of people being diagnosed under the age of 18 is increasing [5].

What are the different types of MS?

MS can be divided into three main types: relapsing remitting MS, secondary progressive MS, and primary progressive MS.

Relapsing remitting MS
For most people with MS, episodes of worsening function (relapses) are initially followed by recovery periods (remissions). This type of MS is called relapsing remitting MS (RMS) [6].Some estimate that around 85% of people with MS have the relapsing remitting form [9]. This means that they will have periods when symptoms flare up aggressively followed by periods of recovery - the remission.

Secondary progressive MS
Secondary progressive MS is a more advanced form of the disease. Studies that have monitored people with MS over a long period of time suggest that in 10 years, half those people who were diagnosed with relapsing remitting MS will have developed secondary progressive MS [8]. Sometime people experience secondary progressive MS when they receive their diagnosis. People's experience of secondary progressive MS can vary widely.

Primary progressive MS
PPMS is characterised by steadily worsening function from the onset of symptoms, often without early relapses or remissions. Estimates place the figure at 10% of MS patients having this form [9].

'Progressive' is the word used to describe the increase in disability in MS. Although disability increases in progressive MS, the rate at which this happens varies from person to person.  

How is MS treated?

There is no cure yet for multiple sclerosis - treatment in this instance refers to focusing on helping patients recover from attacks, slowing the progression, and managing MS symptoms (enhancing quality of life).  

Other treatments to help manage MS symptoms
Alongside the prescription of medications to help manage the severe symptoms of the different types of MS, there are other treatments that an MS specialist can recommend:
  • Physical therapy - This is a process of learning stretching and strengthening exercises, or regular activity like aquatherapy, under the instruction of a physical therapist. Physical therapy can help manage leg weakness and other gait problems often associated with MS [11]
  • Muscle relaxants -  People can experience painful or uncontrollable muscle stiffness or spasms in their limbs and muscle relaxants such as baclofen and tizanidine can be prescribed to help. Contact your physician for more information [15].
  • Other medications - Medications can also be prescribed for fatigue, depression, sexual dysfunction, pain, and bladder or bowel problems that are associated with MS [15].
  • Special diets - Though there is no specific 'MS Diet' [12], for chronic illnesses like MS it is essential to maintain a balanced and healthy diet low in fats and sugars, high in fibre and vegetables. People should consult their physician before using any nutritional supplements or vitamins.

Which medicines are used for MS?

At the top of this page you can find the list of medicines which TheSocialMedwork supplies,  which can be prescribed by doctors for MS patients.

TheSocialMedwork does not make recommendations on which treatment or medication to use. To acquire medication a treating doctor's prescription is needed.

Potential new treatments for MS
MS is a highly researched disease and from the clinical studies there may come new medications. When a new medication is approved by a major regulatory authority, TheSocialMedwork will make it available to patients globally as quickly as possible.

References and Further Reading
  1. https://www.webmd.com/multiple-sclerosis/features/multiple-sclerosis-different-women#1
  2. https://www.ncbi.nlm.nih.gov/pubmedhealth/PMHT0024311/
  3. https://www.mstrust.org.uk/a-z/prevalence-and-incidence-multiple-sclerosis
  4. https://patient.info/health/multiple-sclerosis-leaflet
  5. https://www.mstrust.org.uk/a-z/childhood-ms
  6. https://patient.info/doctor/multiple-sclerosis-pro
  7. https://www.nationalmssociety.org/About-the-Society/Press-Room/MS-the-Disease
  8. http://jnnp.bmj.com/content/67/2/148
  9. https://www.healthline.com/health/multiple-sclerosis/stages
  10. https://www.nationalmssociety.org/What-is-MS/Types-of-MS/Primary-progressive-MS
  11. https://multiplesclerosis.net/treatment/physical-therapy/
  12. https://www.nationalmssociety.org/Living-Well-With-MS/Diet-Exercise-Healthy-Behaviors/Diet-Nutrition
  13. https://www.nationalmssociety.org/What-is-MS/What-Causes-MS/Viruses
  14. https://www.mstrust.org.uk/understanding-ms/ms-symptoms-and-treatments/symptoms
  15. https://www.mssociety.org.uk/what-is-ms/signs-and-symptoms/spasms-and-stiffness/treatment-and-management

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